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Therapy: Pain Management
Vaccination: Vaccines
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Total 118 results found since Jan 2013.
Omega-3 polyunsaturated fatty acids and the psychiatric post-acute sequelae of COVID-19: A one-year retrospective cohort analysis of 33,908 patients
CONCLUSION: Omega-3 PUFAs may require re-evaluation as a preventive strategy against adverse mental health outcomes post-COVID-19 in placebo-controlled clinical trials.PMID:37716377 | DOI:10.1016/j.bbi.2023.09.008
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Ting-Hui Liu Chung-Han Ho Daniel Tzu-Li Chen Jheng-Yan Wu Po-Yu Huang Chih-Cheng Lai Kuang-Yang Hsieh Kuan-Pin Su Source Type: research
Clinical phenotypes and quality of life to define post-COVID-19 syndrome: a cluster analysis of the multinational, prospective ORCHESTRA cohort
EClinicalMedicine. 2023 Jul 21;62:102107. doi: 10.1016/j.eclinm.2023.102107. eCollection 2023 Aug.ABSTRACTBACKGROUND: Lack of specific definitions of clinical characteristics, disease severity, and risk and preventive factors of post-COVID-19 syndrome (PCS) severely impacts research and discovery of new preventive and therapeutics drugs.METHODS: This prospective multicenter cohort study was conducted from February 2020 to June 2022 in 5 countries, enrolling SARS-CoV-2 out- and in-patients followed at 3-, 6-, and 12-month from diagnosis, with assessment of clinical and biochemical features, antibody (Ab) response, Variant o...
Source: Cell Research - September 1, 2023 Category: Cytology Authors: Elisa Gentilotti Anna G órska Adriana Tami Roy Gusinow Massimo Mirandola Jes ús Rodríguez Baño Zaira R Palacios Baena Elisa Rossi Jan Hasenauer Iris Lopes-Rafegas Elda Righi Natascia Caroccia Salvatore Cataudella Zeno Pasquini Thomas Osmo Lidia Del Pi Source Type: research
Experience of Lifetime Health Maintenance Program: An Observational Study of a 30-Year Period of Outpatient Primary Care in a Tertiary Hospital
CONCLUSION: The LHMP emphasized the need to systematize regular primary care physicians in Korea. Policy changes are necessary to strengthen primary care, and the LHMP serves as an intermediate step in organizing regular primary care physicians in Korea.PMID:37582665 | DOI:10.4082/kjfm.23.0023
Source: Pain Physician - August 15, 2023 Category: Anesthesiology Authors: Seo Young Kang Young Sik Kim Source Type: research
Gastrointestinal tract and viral pathogens
World J Virol. 2023 Jun 25;12(3):136-150. doi: 10.5501/wjv.v12.i3.136.ABSTRACTViral gastroenteritis is the most common viral illness that affects the gastrointestinal (GI) tract, causing inflammation and irritation of the lining of the stomach and intestines. Common signs and symptoms associated with this condition include abdominal pain, diarrhea, and dehydration. The infections commonly involved in viral gastroenteritis are rotavirus, norovirus, and adenovirus, which spread through the fecal-oral and contact routes and cause non-bloody diarrhea. These infections can affect both immunocompetent and immunocompromised indiv...
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Gowthami Sai Kogilathota Jagirdhar Yashwitha Sai Pulakurthi Himaja Dutt Chigurupati Salim Surani Source Type: research
Non-pharmacological management of infant and young child procedural pain
CONCLUSIONS: Overall, non-nutritive sucking, facilitated tucking, and swaddling may reduce pain behaviours in preterm born neonates. Non-nutritive sucking may also reduce pain behaviours in full-term neonates. No interventions based on a substantial body of evidence showed promise in reducing pain behaviours in older infants. Most analyses were based on very low- or low-certainty grades of evidence and none were based on high-certainty evidence. Therefore, the lack of confidence in the evidence would require further research before we could draw a definitive conclusion.PMID:37314064 | DOI:10.1002/14651858.CD006275.pub4
Source: Cochrane Database of Systematic Reviews - June 14, 2023 Category: General Medicine Authors: Rebecca R Pillai Riddell Oana Bucsea Ilana Shiff Cheryl Chow Hannah G Gennis Shaylea Badovinac Miranda DiLorenzo-Klas Nicole M Racine Sara Ahola Kohut Diana Lisi Kara Turcotte Bonnie Stevens Lindsay S Uman Source Type: research
Top 100 Most-Cited Papers in Herpes Zoster from 2000 to 2022: A Bibliometric Study
CONCLUSION: In terms of the quantity of T100 articles, researchers, and organizations, the US is the predominant country. The most T100 papers were published in the special journal Clinical Infectious Diseases. The most academic focus remain the remedies for postherpetic neuralgia and vaccine development for individualized groups.PMID:37273270 | PMC:PMC10237222 | DOI:10.2147/JPR.S409616
Source: Herpes - June 5, 2023 Category: Infectious Diseases Authors: Ning Gao Meng Li Weiming Wang Lei Wang Zhen Liu Yufeng Guo Source Type: research
TREMFYA ® (guselkumab) Real-World Data Analyses Show Greater Treatment Persistence Than IL-17s in Both Bio-naïve and Bio-experienced Patients Living With Moderate to Severe Plaque Psoriasis
SPRING HOUSE, PENNSYLVANIA, March 17, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data, showing that initiation of TREMFYA® (guselkumab) was associated with greater treatment persistencea compared to secukinumab or ixekizumab in bio-naïve and bio-experienced patientsb living with moderate to severe plaque psoriasis (PsO), based on pairwise analysesc of real-world data.[1],[2] Additionally, in a post-hoc analysis of Phase 3 VOYAGE 2 clinical trial results, TREMFYA demonstrated durable clinical efficacy, itch relief and quality-of-life improvements in patients living with scal...
Source: Johnson and Johnson - March 17, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Juvenile Idiopathic Arthritis for the General Practitioner
This article discusses the differences between inflammatory and noninflammatory joint pain, the diagnosis and various categories of JIA, long-term outcomes and complications associated with JIA, and the general management of JIA with special emphasis on adverse effects and contraindications of therapies.PMID:36854831 | DOI:10.1542/pir.2021-005456
Source: Pain Physician - February 28, 2023 Category: Anesthesiology Authors: Alexandra Theisen Stacey E Tarvin Source Type: research
Herpes zoster after COVID-19 vaccination, aspect of pain medicine: a retrospective, single-center study
CONCLUSIONS: COVID-19 vaccination-related HZ showed clinical features similar to those ofthe other HZ.PMID:36746903 | DOI:10.17085/apm.22207
Source: Herpes - February 6, 2023 Category: Infectious Diseases Authors: Ji Hye Lee Yu Yil Kim Hyun Joo Heo Ji Hun Park Hyung Gu Cho Geonbo Kim Source Type: research
Computer-aided drug design for the pain-like protease (PL < sup > pro < /sup > ) inhibitors against SARS-CoV-2
This report used pharmacophore-based drug design technology to identify potential compounds as PLpro inhibitors against SARS-CoV-2. The optimal pharmacophore model was fully validated using different strategies and then was employed to virtually screen out 10 compounds with inhibitory. Molecular docking and non-bonding interactions between the targeted protein PLpro and compounds showed that UKR1129266 was the best compound. These results provided a theoretical foundation for future studies of PLpro inhibitors against SARS-CoV-2.PMID:36689835 | DOI:10.1016/j.biopha.2023.114247
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - January 23, 2023 Category: Drugs & Pharmacology Authors: Hongwei Gao Renhui Dai Ruiling Su Source Type: research
